Airfoil wake vortex characteristics in the far field

Tangential and axial velocity profiles were measured in the far field wake vortices of several different airfoils. The results are summarized and discussed. A scanning laser velocimeter was used to obtain data up to 1000 chord lengths behind airfoils with rectangular, diamond-shaped, and swept wing planforms at several different angles of attack. The results show general agreement with wind tunnel measurements made in the near field. The results identify two separate flow regions for the dependence of vortex maximum tangential velocity on downstream distance; an inviscid region where the velocity remains constant after rollup to downstream distances of 200 chord lengths, and then a decay or viscous region that persisted to the limit of the test distance. The decay rates appear to be sensitive to both angle of attack and span loading. The maximum tangential velocity for downstream distances to 40 span lengths was reduced by a factor of 2 by changing from an elliptic (swept wing) or rectangular span loading to a triangular-like span loading (diamond-shaped planform wing). Measured axial velocity defects are shown to agree with those predicted by laminar theory

A low power routing algorithm for localization in IEEE 802.15.4 networks

Many context-aware applications rely on the knowledge of the position of the user and the surrounding objects to provide advanced, personalized and real-time services. In wide-area deployments, a routing protocol is needed to collect the location information from distant nodes. In this paper, we propose a new source-initiated (on demand) routing protocol for location-aware applications in IEEE 802.15.4 wireless sensor networks. This protocol uses a low power MAC layer to maximize the lifetime of the network while maintaining the communication delay to a low value. Its performance is assessed through experimental tests that show a good trade-off between power consumption and time delay in the localization of a mobile device

Experimental evaluation of IEEE 802.15.4/ZigBee for multi-patient ECG monitoring

IEEE 802.15.4/ZigBee wireless sensor networks (WSNs) are a promising alternative to cabled systems for patient monitoring in hospitals. Some areas where monitoring systems based on WSNs can be successfuly used are ambulatory, waiting and triage rooms, post-op, and emergency rooms. The low power and small size ZigBee devices have the ability to form self-configuring networks that can extend themselves through a hospital wing or floor. Using spatially distributed networks, it is possible to cover an extended area and serve several patients. However, the low data rate protocols provided by IEEE 802.15.4 poses several challenges, mainly because its protocols were primarily designed to operate in low traffic load scenarios but some vital signs sensors generate a large volume of data. This work presents an experimental evaluation of the performance of multi-hop ZigBee networks comprised of several nodes that carry the traffic of wearable electrocardiogram (ECG) sensors. The results indicate that star networks can relay 100% of the traffic generated by at least 12 ECG nodes. In tree topologies, the increase of the network traffic load reduces the performance but even these networks can reliably relay the traffic of a considerable number of ECG nodes.Fundação para a Ciência e a Tecnologia (FCT)Grupo AMI – Assistência Médica Integral (Casa de Saúde Guimarães, SA

Clinical performance of methylation as a biomarker for cervical carcinoma in situ and cancer diagnosis: A worldwide study.

The shift towards primary human papillomavirus (HPV)-based screening has necessitated the search for a secondary triage test that provides sufficient sensitivity to detect high-grade cervical intraepithelial neoplasia (CIN) and cancer, but also brings an improved specificity to avoid unnecessary clinical work and colposcopy referrals. We evaluated the performance of the previously described DNA-methylation test (S5) in detecting CIN3 and cancers from diverse geographic settings in high-, medium- and low-income countries, using the cut-off of 0.80 and exploratory cut-offs of 2.62 and 3.70. Assays were performed using exfoliated cervical specimens (n = 808) and formalin-fixed biopsies (n = 166) from women diagnosed with cytology-negative results (n = 220), CIN3 (n = 204) and cancer stages I (n = 245), II (n = 249), III (n = 28) and IV (n = 22). Methylation increased proportionally with disease severity (Cuzick test for trend, P < .0001). S5 accurately separated women with negative-histology from CIN3 or cancer (P < .0001). At the 0.80 cut-off, 543/544 cancers were correctly identified as S5 positive (99.81%). At cut-off 3.70, S5 showed a sensitivity of 95.77% with improved specificity. The S5 odds ratios of women negative for cervical disease vs CIN3+ were significantly higher than for HPV16/18 genotyping at all cut-offs (all P < .0001). At S5 cut-off 0.80, 96.15% of consistently high-risk human papillomavirus (hrHPV)-negative cancers (tested with multiple hrHPV-genotyping assay) were positive by S5. These cancers may have been missed in current primary hrHPV-screening programmes. The S5 test can accurately detect CIN3 and malignancy irrespective of geographic context and setting. The test can be used as a screening and triage tool. Adjustment of the S5 cut-off can be performed considering the relative importance given to sensitivity vs specificity

An Experimental Evaluation of Position Estimation Methods for Person Localization in Wireless Sensor Networks

In this paper, the localization of persons by means of a Wireless Sensor Network (WSN) is considered. Persons carry on-body sensor nodes and move within a WSN. The location of each person is calculated on this node and communicated through the network to a central data sink for visualization. Applications of such a system could be found in mass casualty events, firefighter scenarios, hospitals or retirement homes for example. For the location estimation on the sensor node, three derivatives of the Kalman Filter and a closed-form solution (CFS) are applied, compared, and evaluated in a real-world scenario. A prototype 65-node ZigBee WSN is implemented and data are collected in in- and outdoor environments with differently positioned on-body nodes. The described estimators are then evaluated off-line on the experimentally collected data. The goal of this paper is to present a comprehensive real-world evaluation of methods for person localization in a WSN based on received signal strength (RSS) range measurements. It is concluded that person localization in in- and outdoor environments is possible under the considered conditions with the considered filters. The compared methods allow for suffciently accurate localization results and are robust against inaccurate range measurements

Refractive Index Matched Scanning of Dense Granular Materials

011301Biological and Soft Matter Physic